Overview Nobivac® Lepto4 has been shown to be effective for vaccination of healthy dogs 8 weeks of age or older against Leptospira canicola, L. icterohaemorrhagiae, L. pomona, and L. grippotyphosa. Duration of immunity has not been established. This product has also been shown to be effective against mortality and leptospiruria (shedding of Leptospira in the urine) caused by L. canicola, L. icterohaemorrhagiae, L. pomona, and L. grippotyphosa.

  • Protects against liver dysfunction and thrombocytopenia3
  • The only vaccine shown to be 100% effective against mortality and urinary shedding of all 4 serovars